Human iPSCs for Modeling Primary Tauopathies
| Donor ID | Alternative Donor ID | Mutation | Clinical Status* | Autopsy | Corrected Line | Fibroblast Source° | Neural Induction |
| FTD-FF | 151209SBA1 | A152T/WT | S | Pending | No | UCSF | Yes |
| FTD-T | 151209SBA2 | A152T/WT | S | PSP | No | UCSF | Yes |
| GIH2 | 151209SBA3 | A152T/WT | A | N/A | No | UCSF | Yes |
| FTD38 | 151209SBA4 | A152T/WT | A | N/A | No | UCSF | Yes |
| GIH169 | 160311SBA5 | A152T/WT | S | N/A | No | UCSF | Yes |
| GIH56 | 160311SBA6 | A152T/WT | S | N/A | No | UCSF | Yes |
| Tau1225-7 | 160311SBA7 | A152T/WT | S | CBD | No | UCSF | Yes |
| F0510 | F0510 | P301L/WT | A | N/A | Yes | NINDS Repository | Yes |
| F13535 | F13535 | P301L/WT | A | N/A | No | WUSM | N/A |
| F14537 | F14537 | P301L/WT | S | FTLD-Tau | No | WUSM | N/A |
| F14536 | F14536 | WT/WT# | A | N/A | No | WUSM | N/A |
| MHF110 | 17524NCE1 | S305I/WT | S | N/A | No | UCSF | N/A |
| 75.11-Temporarily unavailable | AG255075 | S305I/WT | N/A | N/A | Yes | ARTFL/LEFFTDS | N/A |
| 300.12-Temporarily unavailable | AG251300 | S305N/WT | N/A | N/A | No | ARTFL/LEFFTDS | N/A |
| GP1.1 | GP-1i | S305S/WT | N/A | N/A | Yes | NSWBB | N/A |
| GIH36 | 160311SBC1 | IVS10+16/WT | A | N/A | Yes | UCSF | Yes |
| GIH161 | I18XXYYNCG1 | WT/WT# | A | N/A | No | UCSF | N/A |
| GIH178 | I18XXYYNCC3 | IVS10+16/WT | N/A | N/A | No | UCSF | N/A |
| GIH6 | 160311SBB1 | V337M/WT | S | FTLD-Tau | Yes | UCSF | Yes |
| GIH7 | 160311SBB2 | V337M/WT | A | N/A | Yes | UCSF | Yes |
| GIH155 | 160311SBB3 | V337M/WT | S | N/A | No | UCSF | N/A |
| ND32951A | ND32951A | V337M/WT | A | N/A | Yes | NINDS Repository | Yes |
| MHF100 | 171018NCD1 | G389R/WT | A | N/A | No | UCSF | N/A |
| MHF101 | 171018NCD2 | G389R/WT | A | N/A | No | UCSF | N/A |
| MHF102 | 171018NCD3 | G389R/WT | S | N/A | No | UCSF | N/A |
| F11374 | F11374 | R406W/WT | A | N/A | No | WUSM | N/A |
| F11362 | F11362 | R406W/WT | S | FTLD-Tau | Yes | WUSM | Yes |
| F11421 | F11421 | R406W/WT | A | N/A | Yes | WUSM | Yes |
| GIH143 | UCSF1 | R406W/R406W | S | N/A | No | UCSF | N/A |
| GIH131 | 170524NCF1 | WT/WT | S | PSP | No | UCSF | N/A |
| GIH92 | 171013NCF3 | WT/WT | S | PSP | No | UCSF | N/A |
*At biopsy; A, Asymptomatic. S, symptomatic. #, Non-carrier, related to MAPT family. °UCSF, University of California San Francisco Memory and Aging Center. WUSM, Washington University, Knight Alzheimer’s Disease Research Center. NINDS Repository, National Institute of Neurologic Disorders and Stroke. ARTFL/LEFFTDS, Advancing Resource and Treatment for Frontotemporal Dementia/Longitudinal Evaluations of Familial Frontotemporal Dementia Subjects. NSWBB, New South Wales Brain Bank. N/A, not available.
Please refer to our recent publication for more information:
https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(19)30335-2