New Scientific Findings Published
Publications are how scientists communicate their findings to the rest of the scientific community and are an important part of the scientific process. This year didn’t start off ROCK-y, when Drs. Xiuli Zhao and Liz Fisher published their paper on the regulation of neural stem cell motility in the aging mouse subventricular zone by the RHO-ROCK pathway. Their work was also the focus of the podcast, The Stem Cell Report, hosted by Dr. Martin Pera. Dr. Zhao was also the first author of a paper from work in her previous lab which was published earlier this year.
Dr. Temple co-authored two collaborative reviews and reports this year. The first focused on outlining common mechanisms in neurodegeneration, and the future of projects to prevent neurodegeneration and treat and prevent vision loss. The second paper established a consensus on the terms used in the topics of organoid and assembloid research. In both papers, Dr. Temple worked with scientific thought leaders to move forward discourse and ideas to solve important problems in the fields of neurodegeneration and stem cells.
Dr. Liz Fisher also published a first-author paper, which identified cross talk between B cells and microglia following spinal cord injury.
Several projects have been published this year which were performed in collaboration with researchers at the NSCI. Dr. Temple’s collaboration with Dr. Celeste Karch at Washington University in St. Louis led to a publication on proteostasis deficits in induced pluripotent stem cell models of frontotemporal lobar dementia. Dr. David Butler and Dr. Temple published a paper with Dr. Bess Frost at UT Health San Antonio, on Tau intrabody therapeutics in Drosophila. Susan Goderie, Taylor Bertucci, Shona Joy, Steve Lotz, Sue Borden, and Sally Temple collaborated with Dr. Ken Kosik at UC Santa Barbara on Tau mutations inducing cholesterol homeostasis problems in cerebral organoids, which resulted in a publication in Stem Cell Reports. Drs. Anne Messer and David Butler published a paper with Dr. Jeff Kordower advancing AAV technology in transducing neural cells in adult rats. Dr. Butler also published work on erythrosin B as an antiviral against Zika virus in collaboration with Dr. Hongmin Li.
Drs. Taylor Bertucci, Meysam Yazdankhah, Liz Fisher, Kate Tubbesing and Brigitte Arduini all contributed to work led by external partners and previous labs published this past year. Great work, everyone!